ISBE.NL @ O|2, First Floor, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands, EU
ISBE@NL
Research Infrastructure Systems Biology Europe, NL branch
Crowning Corona policies: Understanding and modelling COVID-19 epidemics
A crash course for learning to use models to better understand and assess COVID-19 policies around the world
30 November - 9 December 2020 (online)
Under the auspices of the research infrastructure for systems biology and bioinformatics ISBE.NL and ELIXIR.Luxembourg
Aim:
After this course, participants will be able to model the Corona epidemics themselves and assess governmental and other policies critically
For further details: elixir-luxembourg.org/events/2020_11_30_COVID19_modelling_training
Entry level: any; we will cater for bridging gaps
Welcome to ISBE.NL
The Netherlands' arm of ISBE-Light (the Infrastructure for Systems Biology Europe), ISBE@NL, has started its operation 1 September 2016, with its first service provision:
Make Me My Model
4M 4U: Non modellers can obtain (assistance with) the making of a computational model of their biological system
If interested, please e-mail the executive director Alexey Kolodkin mailto:a.n.kolodkin@vu.nl l)
In March 2018 ISBE.NL has extended to include the groups of Ilja Arts ( Maastricht ), Natal van Riel ( Eindhoven ) and Vitor Martins dos Santos ( Wageningen ) and their expertise
Modelling expertise offered as a service in ISBE.NL:
Systems Biology Amsterdam (Alexey Kolodkin, Hans Westerhoff et al): precise kinetic models of metabolism and signal transduction; metabolic control analysis, hierarchical regulation analysis, non-equilibrium dynamics, statistical mechanics, enzyme kinetics, flux balance analysis. Energy and carbohydrate metabolism in Archaea, Bacteria and human; ammonium assimilation in Bacteria; differential network-based drug design; cancer metabolic rewiring; cell cycle; genome wide metabolic map and inborn errors of metabolism; epigenetics.
Wageningen University (Vitor Martins dos Santos et al): meta-genomics -transcriptomics and –proteomics; analyses of complex communities of the GIT; genome-scale modelling and engineering; reverse engineering and network inference; chassis-circuit interactions; model-driven experimental circuit design; multivariate statistical analysis; defining growth media; vaccine production; drug target identification TB; cell factories; bio-remediation. Further information.
Eindhoven (Natal van Riel et al): Data-driven kinetic and physiological modelling of human metabolism and its regulatory systems; dynamic modelling; parameter estimation; uncertainty quantification; Metabolic Syndrome; liver diseases; diabetes; skeletal muscle energy metabolism. Further information.
Maastricht Centre for Systems Biology (MaCSBio) (Ilja Arts et al): Topics: Systems Medicine of Chronic Diseases: empirical domains of human metabolism, obesity and related diseases such as type 2 diabetes, cardiovascular disease and liver disease; modelling of whole-body and tissue-specific metabolism; unravelling their regulatory processes. Activities: generation and analysis of dynamic models of metabolism; analysis and visualization of genome-scale data using network and pathway approaches, including (genome-scale) metabolic modelling (GSMM); generating complex prediction models through machine learning and statistical inference . Further information.
Read and add acknowledgements for ISBE
Questions, Answers, Comments, Complaints and Suggestions
ISBE@NL joint presentation (Lunteren, May 16, 2018)
See further below
ISBE.NL is part of ISBElight which also offers model and data stewardship services through JWS-online and its component FAIRDOM
Vacancies:
To strengthen MaCSBio’s ongoing research and teaching activities in the field of metabolic modelling, we are looking for an ambitious Assistant or Associate Professor (tenure-track) with experience in dynamic (ODE) models, model fitting and parameter estimation, genome-scale metabolic models (GEMs), and/or integration of omics data into GEMs: https://www.academictransfer.com/en/47652/assistantassociate-professor-in-systems-biology-tenure-track-position/
Systems Biologists eager to make models for you:
Alexey Kolodkin (executive director): Dynamic modelling of signalling and Parkinson's disease
Ablikim Abulikemu: Systems Immunology
Stefania Astrologo: Modelling noise, tumor cell heterogeneity and drug resistance
Matteo Barberis: Cell cycling
Zahid Hassan: Systems ecology and bioremediation
Thierry Mondeel: Map making, Flux Balance Analysis, Microbial Energetics
Samrina Rehman: Functional genomics' data analysis
Yanfei Zhang (UvA): Extremophile energetics
Ewelina Weglarz-Tomczak (UvA): Modelling for ISBE.NL and personalized medicine
Jacky Snoep: data stewardship, modelling, malaria, HIV
Hans V. Westerhoff: Control and regulation analysis, thermodynamics, modelling
plus
ISBE-scientists at the other ISBE nodes in Europe
ISBE.NL is largely based at SystemsBiologyAmsterdam.NL