Research Infrastructure Systems Biology Europe, NL branch

ISBE.NL @ O|2, First Floor, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands, EU

Call Fast: +31 20 5987230

Crowning Corona policies: Understanding and modelling COVID-19 epidemics

A crash course for learning to use models to better understand and assess COVID-19 policies around the world

30 November - 9 December 2020 (online)

Under the auspices of the research infrastructure for systems biology and bioinformatics ISBE.NL and ELIXIR.Luxembourg


After this course, participants will be able to model the Corona epidemics themselves and assess governmental and other policies critically

For further details:

Entry level: any; we will cater for bridging gaps

Welcome to ISBE.NL

The Netherlands' arm of ISBE-Light (the Infrastructure for Systems Biology Europe), ISBE@NL, has started its operation 1 September 2016, with its first service provision:

Make Me My Model

4M 4U: Non modellers can obtain (assistance with) the making of a computational model of their biological system

If interested, please e-mail the executive director Alexey Kolodkin l)

In March 2018 ISBE.NL has extended to include the groups of Ilja Arts ( Maastricht ), Natal van Riel ( Eindhoven ) and Vitor Martins dos Santos ( Wageningen ) and their expertise

Modelling expertise offered as a service in ISBE.NL:

Systems Biology Amsterdam (Alexey Kolodkin, Hans Westerhoff et al): precise kinetic models of metabolism and signal transduction; metabolic control analysis, hierarchical regulation analysis, non-equilibrium dynamics, statistical mechanics, enzyme kinetics, flux balance analysis. Energy and carbohydrate metabolism in Archaea, Bacteria and human; ammonium assimilation in Bacteria; differential network-based drug design; cancer metabolic rewiring; cell cycle; genome wide metabolic map and inborn errors of metabolism; epigenetics.

Wageningen University (Vitor Martins dos Santos et al): meta-genomics -transcriptomics and –proteomics; analyses of complex communities of the GIT; genome-scale modelling and engineering; reverse engineering and network inference; chassis-circuit interactions; model-driven experimental circuit design; multivariate statistical analysis; defining growth media; vaccine production; drug target identification TB; cell factories; bio-remediation. Further information.

Eindhoven (Natal van Riel et al): Data-driven kinetic and physiological modelling of human metabolism and its regulatory systems; dynamic modelling; parameter estimation; uncertainty quantification; Metabolic Syndrome; liver diseases; diabetes; skeletal muscle energy metabolism. Further information.

Maastricht Centre for Systems Biology (MaCSBio) (Ilja Arts et al): Topics: Systems Medicine of Chronic Diseases: empirical domains of human metabolism, obesity and related diseases such as type 2 diabetes, cardiovascular disease and liver disease; modelling of whole-body and tissue-specific metabolism; unravelling their regulatory processes. Activities: generation and analysis of dynamic models of metabolism; analysis and visualization of genome-scale data using network and pathway approaches, including (genome-scale) metabolic modelling (GSMM); generating complex prediction models through machine learning and statistical inference . Further information.

Read and add acknowledgements for ISBE

Questions, Answers, Comments, Complaints and Suggestions

ISBE@NL joint presentation (Lunteren, May 16, 2018)

at ISBE BioSB session

See further below

CORBEL open call has been closed...

Thanks to those who applied!

New call is coming soon!

ISBE.NL is part of ISBElight which also offers model and data stewardship services through JWS-online and its component FAIRDOM


To strengthen MaCSBio’s ongoing research and teaching activities in the field of metabolic modelling, we are looking for an ambitious Assistant or Associate Professor (tenure-track) with experience in dynamic (ODE) models, model fitting and parameter estimation, genome-scale metabolic models (GEMs), and/or integration of omics data into GEMs:

Who we are at ISBE.NL (Amsterdam)

and ISBE.UK-MCISB (Manchester):

Systems Biologists eager to make models for you:

Alexey Kolodkin (executive director): Dynamic modelling of signalling and Parkinson's disease

Ablikim Abulikemu: Systems Immunology

Stefania Astrologo: Modelling noise, tumor cell heterogeneity and drug resistance

Matteo Barberis:  Cell cycling

Zahid Hassan: Systems ecology and bioremediation

Thierry Mondeel: Map making, Flux Balance Analysis, Microbial Energetics

Samrina Rehman: Functional genomics' data analysis

Yanfei Zhang (UvA): Extremophile energetics

Ewelina Weglarz-Tomczak (UvA): Modelling for ISBE.NL and personalized medicine

Jacky Snoep: data stewardship, modelling, malaria, HIV

Hans V. Westerhoff: Control and regulation analysis, thermodynamics, modelling


ISBE-scientists at the other ISBE nodes in Europe

ISBE.NL is largely based at SystemsBiologyAmsterdam.NL

Contact us

We like to answer your questions and to make systems biology models for you

ISBE.NL@ the two collaborating Amsterdam Universities (University of Amsterdam and Vrije Universiteit) Joint UvA-VUA campus

+31 20 - 5987230